I've recently started getting more familiar with Capture One, though I, like many others, used to feel a little intimidated by the interface and enjoyed the comfort zone I could edit in with Adobe programs. This great video shows you how to get started with the program.
The Art of Photography made this helpful video about Capture One. The interface is different than Adobe's. It's a different company, different approach, and focused only on photography, not design or image editing in other graphic art forms. With a couple of minutes browsing around and clicking, it's actually quite easy to understand the workflow they believe a photographer goes through to get their images to a client. The interface is also very customizable, and the power of the right-click on specific areas will open up the application to you and give you quick access to various tools.
The Advantage of Using Capture One vs Lightroom
It might not be clear at first, but the catalogs of Capture One and the way of managing your image library database is a lot more dynamic than that of Lightroom, and you can move it from hard drive to hard drive for archiving or editing, which is typically how a photographer works. Lightroom can slow down due to the way it handles its library, though Capture One does not. I am a professional retoucher, and I need to know my way around Capture One and Photoshop and how to best go between between the two as an on-set retoucher or when I'm back at the studio. This video was a great refresher, and if you're starting out as a retoucher or photographer, it's a great overview to get started with one of the applications used across the industry on a global scale.